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Image Search Results
Journal: Biomaterials Research
Article Title: Repair of Osteoporotic Bone Defects in Rats via the Sirtuin 1-Wnt/β-catenin Signaling Pathway by Novel Icariin/Porous Magnesium Alloy Scaffolds
doi: 10.34133/bmr.0090
Figure Lengend Snippet: Experiments on proliferation, senescence, migration, and osteogenic differentiation of BMSCs. (A) OD values of BMSCs in the control group, ICA group, Mg 2+ group, and ICA+Mg 2+ group on the first day and fourth day of cultivation. (*, P < 0.05; **, P < 0.01). (B) β-Galactosidase staining of the effect of costimulators ICA and Mg 2+ on the aging of BMSCs. (C) Microscopic observation of the effect of costimulators ICA and Mg 2+ on the migration capacity of BMSCs. (D) ALP staining and alizarin red-S (ARS) staining for analyzing the effect of costimulators ICA and Mg 2+ on the osteogenic differentiation of BMSCs.
Article Snippet: ICA and magnesium chloride were added separately to the complete medium of
Techniques: Migration, Control, Staining
Journal: Biomaterials Research
Article Title: Repair of Osteoporotic Bone Defects in Rats via the Sirtuin 1-Wnt/β-catenin Signaling Pathway by Novel Icariin/Porous Magnesium Alloy Scaffolds
doi: 10.34133/bmr.0090
Figure Lengend Snippet: ICA and Mg 2+ costimulate the mRNA expression of proliferation-related genes in rat BMSCs via the SIRT1-Wnt/β-catenin signaling pathway. (A) SIRT1. (B) Wnt1a. (C) Wnt3a. (D) Wnt5a. (E) β-catenin. (F) GSK3β. (G) GM-CSF. *, P < 0.05; **, P < 0.01.
Article Snippet: ICA and magnesium chloride were added separately to the complete medium of
Techniques: Expressing
Journal: Biomaterials Research
Article Title: Repair of Osteoporotic Bone Defects in Rats via the Sirtuin 1-Wnt/β-catenin Signaling Pathway by Novel Icariin/Porous Magnesium Alloy Scaffolds
doi: 10.34133/bmr.0090
Figure Lengend Snippet: ICA and Mg 2+ costimulate the mRNA expression of factors related to osteogenic differentiation of rat BMSCs via the SIRT1-Wnt/β-catenin signaling pathway. (A) SIRT1. (B) Wnt5a. (C) β-Catenin. (D) GSK3β. (E) RUNX-2. (F) BMP-2. *, P < 0.05; **, P < 0.01.
Article Snippet: ICA and magnesium chloride were added separately to the complete medium of
Techniques: Expressing
Journal: Biomaterials Research
Article Title: Repair of Osteoporotic Bone Defects in Rats via the Sirtuin 1-Wnt/β-catenin Signaling Pathway by Novel Icariin/Porous Magnesium Alloy Scaffolds
doi: 10.34133/bmr.0090
Figure Lengend Snippet: ICA and Mg 2+ act synergistically to promote the expression of osteogenic differentiation-related proteins in rat BMSCs via the SIRT1-Wnt/β-catenin signaling pathway. (A) Results of Western blot experiment. (B) Statistical graph of Western blot experiment results. *, P < 0.05; **, P < 0.01.
Article Snippet: ICA and magnesium chloride were added separately to the complete medium of
Techniques: Expressing, Western Blot
Journal: Biomaterials Research
Article Title: Repair of Osteoporotic Bone Defects in Rats via the Sirtuin 1-Wnt/β-catenin Signaling Pathway by Novel Icariin/Porous Magnesium Alloy Scaffolds
doi: 10.34133/bmr.0090
Figure Lengend Snippet: SEM and bulk sample observation of the surface structure of different scaffolds and biosafety of the porous magnesium alloy scaffold. (A) Porous magnesium alloy scaffold and novel ICA/porous magnesium alloy scaffold. (B) Confocal microscopic observation of BMSCs. (C) SEM observation of BMSCs and (D) visceral HE staining after implantation of the porous magnesium alloy scaffold in rats.
Article Snippet: ICA and magnesium chloride were added separately to the complete medium of
Techniques: Staining